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LIONS FOUNDATION OF CANADA DOG GUIDES

Lions Foundation of Canada Dog Guides and its founding program, Canine Vision Canada, was established in 1983. It’s the largest school of its kind in Canada with its training school in Oakville and breeding facility in Breslau.

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KIDNEY TOXICITY (DRUG-INDUCED NEPHROTOXICITY) IN DOGS

Internal picture of toxic kidneys

WHAT IS KIDNEY TOXICITY (DRUG-INDUCED NEPHROTOXICITY)? 

Like human kidneys, a dog’s kidneys balance certain substances in the blood and filter out and excrete the body’s wastes as urine.

Some drugs administered for the purpose of diagnosing or treating another medical disorder may have toxic effects on a dog’s kidneys.

WHEN DRUGS REACH THE BLOOD STREAM

The heart sends traces of the drug to the kidneys to filter out the waste in urine. Drugs can interfere with the blood flow to the kidneys as well as cause dysfunction in the kidneys, decreasing their ability to excrete wastes as urine. A dog’s kidneys can be particularly vulnerable to toxicity because of their role in filtering and excreting drugs.  The kidney damage induced by medication is referred to as drug-induced nephrotoxicity that simply means “toxic to the kidneys”.

RISK FACTORS FOR DRUG-INDUCED NEPHROTOXICITY
There are some factors that can increase chances for this illness:

SYMPTOMS OF DRUG-INDUCED NEPHROTOXICITY
Signs associated with nephrotoxicity may include:

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